Genomic Innovator Award (R35 Clinical Trial Optional)
- Outstanding Investigator Award; RFA-HG-18-006
- Deadlines: October 30, 2018; October 30, 2019; October 30, 2020 (Letter of Intent due 45 days prior)
- This program aims to support researchers to do highly innovative work on important problems in genomics. The PD/PIs should be creative investigators, early in their careers, who are part of consortia, large research groups, or other team-science efforts. They should have New Investigator status and have shown the potential to make important contributions to the field of genomics. PD/PIs will have flexibility to take their research in novel directions as scientific opportunities arise during this award.
U.S. – India Collaborative Vision Research Program (R01 Clinical Trial Not Allowed)
- Deadlines: November 8, 2018; November 8, 2019; November 9, 2020
- This FOA is intended to support collaborations between the U.S. and India that focus on the basic biology, epigenetic, and/or genetics of ophthalmic diseases and visual disorders.
- Applications may include, but are not limited to collaborations addressing the following areas:
- Family based genome wide association studies (GWAS) on available cohorts of consanguineous families from India to identify genetic variants that predispose to both Mendelian and complex forms of eye disease;
- Validation of novel GWAS findings in appropriate animal models;
- Identification of biomarkers that predict and/or assess risk and response to interventions;
- Studies of environmental factors that predict risk of eye diseases such as imprinting and other epigenetic effects;
- Studies to determine the underlying biology of ocular diseases including, AMD, diabetic retinopathy, glaucoma, retinitis pigmentosa, cataracts, myopia and presbyopia;
- Studies focusing on the basic science of neuroplasticity of vision including perceptual learning and adaptation after eye injury;
- Studies of the mechanisms through which environmental pollutants/toxins contribute to ocular diseases and their complications including infection and inflammation;
- Identification of factors that influence the success of corneal transplantation and recovery after surgery.